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The new drug delivery system set to revolutionise the mode of drug administration.
Oral thin films are divided into 2 categories -
Orodispersible films are non-mucoadhesive and are designed to break down immediately upon contact with saliva. There are two kinds of orodispersible films: “orally disintegrating” and “orally dissolving.” Both types immediately disintegrate in the mouth, but dissolve in different areas of the body. Orally disintegrating films, which tend to be poorly water-soluble drugs, disintegrate in the mouth and then are both dissolved and absorbed in the gastrointestinal (GI) tract. In contrast, orally dissolving films are generally water soluble and therefore disintegrate and dissolve simultaneously in the mouth.
Oromucosal films are placed either onto or under the tongue, or on the inside of the cheek. As mucoadhesives, they are designed to adhere to the inside of the oral cavity and release drugs slowly across the mucous membrane (i.e., under the tongue or through cheek) directly into a patient’s systemic circulation
Patented Thinoral® technology yields instantly wettable, rapidly dissolving, non-sticky, non-tacky and non-curving films. Drug loading, as high as 50-60 mg of the active drug. Uniform thinness provides large surface area for dissolution. Alleviate solubility issues of many poorly soluble drugs. Suitable for the delivery of thermolabile drugs.
Patented Thinoral® technology yields instantly wettable, rapidly dissolving, non-sticky, This is the Future of Pharma & Nutraceuticals.
Mucostrip® is a distinctive dosage form, that is not to be swallowed but simply placed on the tongue with no water required for medicine administration. Mucostrip-OTF offers hassle-free administration to non-cooperative patients with its convince of administration anywhere, anytime. It also offers good taste, better palatability, is highly portable and its distinctive dosage form assists better compliance by geriatric patients on multiple drug regimen.
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Mucostrip is a distinctive dosage form, that is not to be swallowed but simply placed on the tongue with no water required for medicine administration. Mucostrip-OTF offers hassle-free administration to non-cooperative patients with its convince of administration anywhere, anytime. It also offers good taste, better palatability, is highly portable and its distinctive dosage form assists better compliance by geriatric patients on multiple drug regimen.
Sublingual - Sublingual administration of drug refers to the placement of drug under the tongue. The sublingual route bypasses the first-pass metabolism and hence facilitates rapid absorption of the drug into the systemic circulation. Drug directly reaches the systemic circulation using blood vessels.
Bilayer-OTF technology provide a potential means of reducing the pill burden for patients as they can administer two or more active pharmaceutical ingredients (APIs) in a single FDC (fixed dose combination) dosage form. Bilayer-OTF has one adhesive layer to ensure drug release through Buccal mucosa and a backing layer that avoids drug release in oral cavity.
Augmenting our OTF platform, our technology development strategy has expanded to include a wide range of technologies such as Nanotechnology in combination with OTF, Oral spray drug delivery and cutting-edge technology for drug content uniformity and suitable for combination drug delivery.
Combination of Nanotechnology and Thin Oral® Technology to improve bioavailability of poorly soluble drugs; targeted for crystalline APIs.
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Technology for drug content uniformity and improving yield of controlled drugs (Opioids) and other potent drugs; suitable for combination drug delivery
-Alternate to Injectable which deliver large molecules like peptides ; hormonal therapy
-Oral spray as a form of delivery – proof of concept completed
-Proprietary technology, non infringing process, patent applied in US, Canada, India, Brazil Etc.
