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In recent years, the pharmaceutical industry has seen significant changes brought about by technology. With unhealthy lifestyles on the rise, coupled with the ever increasing number of diseases, the necessity to develop pharmaceutical products at scale, and at speed, demands new-age technology in production processes.Although we cannot deny that the pharmaceutical industry has come a long way in the past couple of decades, there’s still a lot of scope for development.
Here are the top 3 trends in pharmaceutical formulation development that you can expect to see in the year 2023:
1. Better Processes for Protein Purification
Proteins are the active ingredients of several pharmaceutical drugs. One of the greatest challenges that the drug manufacturers face is that proteins derived from organic sources are not derived in their pure forms.
Itis one of the drug developers' primary concerns to make this purification process more efficient so that active ingredients are found in purer forms.Technological advancement in the field can transform this area of drug manufacturing. There are also attempts to make highly concentrated active proteins that can be used subcutaneously to ensure more efficient treatment.
2. Improving Solubility of Poorly-Soluble APIs
Low solubility of pharmaceutical proteins is yet another challenge that the pharmaceutical industry faces. Even when the protein is purified and extracted n its purest form, there is a high chance that it would not be soluble. For assimilation into the human body, protein needs to be soluble in the medium.This is one of the major concerns for those drugs that are orally administered.They should be perfectly soluble in both - the medium they are manufactured in and in the gastrointestinal tract of the human body. This is to ensure that the blood plasma can assimilate them to reach the desired circulation levels.
In the year 2023, there will be greater emphasis on making these active pharmaceutical ingredients more soluble in the solvents by changing their physical or chemical composition without affecting their potency against the condition of the human body. It is still under experimentation to determine which physical or chemical methods will be most suitable for making the drugs more soluble
Even though the pharmaceutical industry has picked up a considerable pace regarding pharmaceutical formulation development,several factors slow down the development process and prevent the pharmaceutical industry from reaching its true potential. The pharmaceutical Industry must adhere to several regulatory norms for the benefit and safeguarding of the public before introducing any novel technology or drug.Even though it accesses a speed breaker in the process, it also checks the manufactured drugs, which is a necessity.
Itis quite satisfactory to see how the pharmaceutical industry is incorporating different aspects of technological advancements within itself with leaps and bounds for the benefit of humankind. It is expected that more and better developments will take place shortly.
With the ever widening scope of science and technology that aims to help the humankind and make the health standards better, the pharmaceutical industry is sure to be affected more in the coming years. This means that there will be a more sophisticated process of production and drug administration with every passing year. Owing to the fact that lifesaving drugs and processes are produced solely by the pharmaceutical companies- such developments greatly affect the health of the entire population of the world.
ZIM Labs is an innovative drug delivery solution provider focusing on improving patient convenience and adherence to drug intake. We offer a range of technology-based drug delivery solutions and non-infringing proprietary manufacturing processes for the production and supply of innovative and differentiated generic pharmaceutical products to our customers globally. AtZIM Labs we provide our customers a comprehensive range of value-added solid dosage differentiated generic products in semi-finished and finished categories/formulations. These include granules, pellets (immediate, sustained,modified and extended-release), taste-masked powders, suspensions, tablets,capsules, and recently developed Oral Thin Films (OTF).
